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Immuno oncology: Local cytokines expression in tumors such as IL-23, IL-36γ, and T-cell co-stimulator OX40L induces tumor regression both locally and systemically.
Immuno-modulation: Transient expression of IL-10 as immune suppressor, TGF beta, co-inhibitor expressions (CD80, CD86, PDL1) is a safe and easy way to modulate the functions of the immune system.
Immunotherapies
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